肝动脉化疗栓塞治疗中晚期肝癌的临床分析

Clinical Analysis of Middle-Late Stage Liver Cancer Treated by Transcatheter Arterial Chemoembolization

目的:通过中晚期肝癌患者的肝动脉化疗栓塞(TACE)的临床观察,探讨该方法的临床应用价值。方法:采用seldinger技术,经皮股动脉插管进行肝动脉灌注化疗药物加栓塞剂。结果:通过对241例患者随访,治疗后4～6周复查CT、B超肿块有不同程度缩小,AFP降低至原来数值的50%以下占68%。本组患者治疗后1、2、3年生存期分别为65.3%、27.2%、10.1%。平均生存期为17.6个月。结论:肝动脉化疗栓塞(TACE)治疗中晚期肝癌是一种有效方法,虽属姑息治疗,但可减轻症状,延长生命。

Objective:To study the clinical value of transcatheter arterial chemoemboliza-tion(TACE).Methods:Transcatheteral hepatic artery perfusion of chemotherapeutic and embol-ic agents via femoral artery was performed by Seldinger technique.Results:After4～6weeks postoperative follow up of241cases,the size of tumors shrinked in some extent by CT and ul-trasonic examination.The AFP value decreased a half of the original level in68%patients.The1-,2-3-year survival rates were65.3%,27.2%and10.1%respectively,and the mean sur-vival time was17.6months.Conclusion:The study suggest that TACE is an effective method for middle-late stage liver cancer patients.Although it is a palliative treatment,yet it can abate the clinical symptoms and prolong the survival time of the patients.