辐射诱发的旁效应研究

Study on bystander effects induced by radiation

辐射能使受照细胞产生基因突变、基因表达水平改变、细胞生长改变等多种生物学效应 ,但研究发现 ,类似的反应在与受照细胞共同培养的未受照细胞中也能发生 ,即产生了旁效应。目前对于旁效应发生机制的了解还很少 。

Radiation can cause a lot of biological effects in irradiated cells, such as mutations,changes of gene expression, cell growth and so on. But these effects can also be observed in non irradiated cells. This phenomenon is termed as bystander effect. Up to now, the mechanisms of bystander effects have been known very little. It is believed that extracellular factors or intercellular communications play a very important role in the process.