奥美拉唑静滴治疗新生儿上消化道出血42例

42 Cases gastric hemorrhage of newborn infant treated with omeprazol (Losec) intravenous infusion

目的：观察奥美拉唑（洛赛克）静脉滴注与西咪替丁静脉滴注治疗新生儿上消化道出血疗效比较。方法：奥美拉唑0.6-0.8mg/kg，每日一次静脉滴注。结果：治疗组42例有效率95.2%，对照组42例有效率45.2%，两组疗效比较（P<0.01)有显著性差异。结论：奥美拉唑静脉滴注治疗新生儿上消化道出血。作用迅速持久，疗效显著。在治疗剂量内未发现明显不良反应。

Objective: Compare observed to two groups gastric hemorrhage of newborn infants treated with omeprazol (Losec) and cimetidine intravenous infusion. Methods: Omeprazol 0. 6 ~ 0. 8 mg/kg intravenous infusion once every day. Results: 40 Cases have more effect in 42 observed group and effect rate were 95. 2% , 19 cases have more effect in 42 control group and effect rate were 45. 2%. Compare with two groups ( P < 0. 01) effect different significantly. Conclusion: Gastric hemorrhage of newborn infant treated with omeprazol intravenous infusion cease the bleeding more quickly and continuously so more effect, we have no found any side - effect in treated usual dosage.