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阿尔茨海默病等痴呆疾病的脑功能影像学研究 被引量：2

Functional neuroimaging of Alzheimer's disease and other dementias
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摘要 痴呆类疾病可分为阿尔茨海默病 (AD)、皮克病、多发性梗死性痴呆 (MID)等类型 ,它们各具不同的临床特点。神经心理学检查对痴呆的诊断及鉴别诊断起一定作用。AD等痴呆疾病的神经影像学发展越来越迅速 ,其中1 8F- FDG PET脑功能显像技术可以早期发现 AD患者大脑皮层顶、颞叶等区域葡萄糖代谢率降低 ,并且左、右半球不对称。 1 8F- FDG PET方法还可以鉴别诊断 Dementing illnesses comprise Alzheimer's disease(AD), Pick's disease, Multi infarct dementia(MID) and other neurological disorders. These diseases have different clinical characters respectively. Neuropsychological examinations can help to diagnose and differential diagnose dementias. The development of neuroimaging dementias is more and more rapid. 18 F FDG PET method shows neocortical hypometabolism occurring in the biparietotemporal lobes and left right asymmetry of AD patients in the early stage . It can also differential diagnose AD from other dementias.
作者 王瑞民
机构地区 中国人民解放军总医院核医学科
出处 《国外医学（放射医学核医学分册）》 2001年第5期209-212,共4页 Foreign Medical Sciences(Section of Radiation Medicine and Nuclear Medicine)
关键词 阿尔茨海默病 痴呆 脑功能影像 ^18F-氟代脱氧葡萄糖 SPECT Alzheirmer's disease dementias functional neuroimaing 18 F FDG PET
分类号 R749.16 [医药卫生—神经病学与精神病学] R816.1 [医药卫生—放射医学]
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参考文献11

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同被引文献10

  • 1吴树亮,金连弘,李竹琴,闫彬彬,田波,于宏伟.阿尔茨海默氏病动物模型的建立[J].解剖科学进展,2004,10(2):109-111. 被引量：5
  • 2林炎松.A1zhe1mer病[A].见:王世真主编.分子核医学[C].北京:中国协和医科大学出版社,2001.359—364.
  • 3百濑敏光.痴呆的SPECT(金丽娟摘译)[J].国外医药：神经病学神经外科学分册,1993,20(4):265-266.
  • 4Hiroshi T, Daniel Y, Masanori I, et al. PET imaging of brain with the β-amyloid probe, [ ^11C] 6-OH-BTA-1 , in a transgenic mouse model of Alzheimer' s disease[ J]. Euro J Nucl Med Mol Imag, 2005,32:593-600.
  • 5Steven N, Victor L, Villemagne, et al. Visual assessment versus quantitative assessment of ^11c-pib PET and f-fdg PET for detection of Alzheimer' s disease[ J ]. J nucl med, 2007,48 : 547-552.
  • 6Agneta N. PET imaging of amyloid in Alzheimer' s disease [ J]. Lancet Neurol, ,2004,3:519-527.
  • 7李坤成.阿茨海默病的影像学诊断[J].国外医学（临床放射学分册）,1997,20(4):226-228. 被引量：1
  • 8徐雁,李舜伟.PET与Alzheimer病诊断[J].基础医学与临床,1999,19(4):22-24. 被引量：3
  • 9刘萍.阿尔茨海默病的非神经系统生物学诊断指标研究进展[J].国外医学（老年医学分册）,2000,21(6):253-256. 被引量：1
  • 10潘中允.临床核医学进展(一)[J].国外医学（放射医学核医学分册）,1991,15(2):74-82. 被引量：10

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国外医学（放射医学核医学分册）
2001年 第5期

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