急性心肌梗死与心绞痛患者血清胆红素水平的比较

Comparison of serum bilirubin level in patients with angina pectoris and acute myocardial infarction

目的 探讨心绞痛和急性心肌梗死患者血清胆红素的差异。方法 收集符合1979年WHO诊断标准的心绞痛(AP)患者71例,急性心肌梗死(AMI)患者61例,其中单纯前壁AMI 11例,下壁AMI 14例。采清晨空腹静脉血测定血清总胆红素(Tbil)、直接胆红素(Dbil)、间接胆红素(Ibil)浓度并进行比较。结果 AMI组各型血清胆红素(Tbil 14.56±6.46μmol/L,Dbil 6.20±2.71μmol/L,Ibil 8.31±4.66μmol/L)均高于AP组(Tbil 11.25±4.79μmol/L,Dbil 4.94±1.82μmol/L,Ibil 6.25±3.99μmol/L),P<0.01。前壁AMI患者血清胆红素水平(Tbil 15.99±8.79μmol/L,Dbil 6.88±4.99μmol/L,Ibil 9.11±5.12μmol/L)较下壁AMI患者血清胆红素水平(Tbil 12.34±2.86μmol/L,Dbil 5.15±0.81μmol/L,Ibil 7.18±2.32μmol/L)高,但无统计学差异(P>0.05)。结论 AMI患者与AP患者血清胆红索水平存在显著性差异,但前壁AMI患者与下壁AMI患者血清胆红素水平的差异无统计学意义。

Objective To explore the difference of serum bilirubin in patients with angina pectoris (AP) and acute myocardial infarction (AMI). Methods Serum bilirubin was measured in 71 patients with AP and 61 patients with AMI (Anterior MI 11 cases and Inferior MI 14 cases). T-test was used to compare the two groups. Results Serum bilirubin in patients with AMI(Tbil 14. 56±6. 46μmol/L,Dbil 6. 20±2. 71μmol/L,Ibil 8. 31±4. 66μmol/L)was high than in the patients with AP (TbiL 11. 25±4. 79μmol/L,Dbil 4. 94±1. 82μmol/L,Ibil 6. 25±3. 99μmol/L),P <0. 01 Serum bilirubin in patients with Anterior MI (Tbil 15. 99±8. 79μmol/L,Dbil 6. 88±4. 99μmol/L,Ibil 9. 11 ±5. 12μmol/L)was high than in the patients with Inferior MI(Tbil 12. 34±2. 86μmol/L,Dbil 5. 15±0. 81μmol/L, Ibil 7. 18±2. 32μmol/L)but there weren't statistically significance. (P>0. 05). Conclusions There were significant differences between serum bilirubin in patients with AMI and that in patients with AP. However there weren't differences between serum bilirubin in patient with inferior myocardial infarction and that in anterior myocardial infarction.