慢性支气管炎急性发作期患者T淋巴细胞亚群的研究

Studies on T Lymphocyte in the Critical Cases with Chronic Bronchitis at the Attack Stage

对慢性支气管炎急性发作期和缓解期患者体内 T淋巴细胞亚群进行研究 .用荧光单抗CD4 +、CD8+/CD2 8-,CD8+/CD2 8+对 T淋巴细胞亚群进行标记和计数 .检测结果显示慢性支气管炎急性发作期患者体内 CD4 +无明显变化 ;CD8+/CD2 8-增加 ;CD8+/CD2 8+减少 .我们认为慢性支气管炎急性期患者 T淋巴细胞亚群变化造成免疫功能紊乱 .因此在治疗疾病过程中 ,除对症处理外 ,另须配合使用提高免疫功能药物 。

To study the T subtype of lymphocytes in the critical cases with chronic bronchitis at the attack and relieved stage . T subtype of lymphocytes was marked and counted with mono antibodies CD 4 +,CD 8 +/CD 28 -, CD 8 +/CD 28 +. In chronic bronchitis cases, CD 4 + had no obvious changes; CD 8 +/CD 28 - was increased. CD 8 +/CD 28 + was decreased. In chronic bronchitis cases, the immune functions were disordered with the result of T subtype of lymphocytes changes, which means that supplement metheds of the disease, should be involved in the treatment improve to improve the immune functions of the patients.