神经桥接材料与周围神经修复

Graft material for repair of peripheral nerve

周围神经损伤的长段缺损需要神经移植修复。自体神经移植一直被认为是桥接周围神经缺损最好的方法 ,但其来源有限 ,且存在供区并发症。最近研究表明 ,神经移植可以通过不同的桥接材料来完成。这些周围神经桥接体 ,作为一种调节和改变神经再生的细胞和分子环境的载体 。

Peripheral nerve lesions with a long segment defect need a grafting conduit to repair. Autogenous nerve grafts is still considered the best material for bridging nerve defects, but it is accompanied by some disadvantages, including insufficient graft material for the reconstruction of a large mixed nerve and complications setting in the site of donor. The results of this research demonstrate that the nerve grafting can be completed by using different bridging material. These peripheral nerve bridges as vehicle for moderation and modulation of the cellular and molecular ambience for nerve regeneration have different effects on the repair for peripheral nerve injury.