基因组范围的蛋白质功能研究方法初探

Primary Research on Genome-wide Protein Function

基因组大规模测序的进展使人们获得了大量新基因数据 ,对这些数据进行基因组范围的规模化功能分析的新方法应运而生 .对其中的结构域融合分析法、系统进化特征法、簇分析法 ,结构分析法 。

Large amount of genome data has been obtained from the rapid progress of genome sequencing. Along with this trend, many new approaches for the study of protein function have been invented. A brief introduction and discussion of those methods such as domain fusion analysis, protein phylogenetic profiles, cluster analysis, protein structure analysis, insertional mutagenesis and the combined algorithm for genome-wide prediction of protein function is reviewed.