抗凝血灭鼠剂对家栖鼠的抗药性和药效比较

Comparison of Anticoagulant Rodenticide Resistance and Effect to Commensal Rodent

目的 :探讨家栖鼠对抗凝血灭鼠剂的抗药性及毒效。方法 :有选择性和无选择性摄食试验。结果 :10年来圻春 3种家栖鼠抗性发生率无大变化 ,反而试鼠的纯药平均致死剂量明显下降 ,但平均致死天数有所延长。4种抗凝血灭鼠剂对褐家鼠的毒杀率均在 91%以上 ,单个笼养和围栏群养摄食系数依次为杀鼠迷 0 .85和 1.5 8、溴敌隆 0 .76和 0 .6 9、杀鼠灵 0 .38和 0 .31、敌鼠钠盐 0 .35和 0 .2 5。结论 :两次抗性测定均表明圻春 3种家栖鼠对抗凝血灭鼠剂具有高度敏感性 ,无抗药性种群发生 ,4种灭鼠剂对褐家鼠均有较高的毒杀效果 ,其中以杀鼠迷的适口性最好。

Objective:To study the resistance and different effect of anticoaglant rodenticide. Methods:Tests of optional and nonoptional taking food.Results:Resistance of three commensal rodent species was not difference for the ten years in Qichun.However,average rate lethal dose of pure drug to tested rodent was obvious drop,average lethal dates were prolong. Killed rate of four anticoagalant rodenticides to Rattus norvegicus was up to 91%,Taking food coefficient at single coop and crovd fence for coumatetralyl were 0.85 and 1.58 respectively;for Bromodiolone were 0.76 and 0.69 respectively, for warfarin were 0.38 and 0.31,for Diphacine Sodium Sait were 0.35 and 0.25. Conclusion:Two tests of anticoagalant shewed that the anticogalant susceptibility for the three species commensal rodent was high in Qichun,and resistance was not happened.The killed rate of the four rodenticide to Rattus norvegicus was high,and the palatable taste of coumatetpalyl was the best in the four species rodicide.