中西医结合治疗原发性肾病综合征180例观察

Integrated traditional Chinese medicine and Westernmedicine in treatment of Primary nephrotic syndrome

目的 :为了探讨原发性肾病综合征 (PNS)的治疗措施 ,提高其疗效。方法 :将 1995年 3月～ 2 0 0 0年 3月PNS患者随机分组 ,进行分析研究。结果 :(1)中西医结合组完全缓解 6 3.89% ,部分缓解 2 4.44 % ,总有效率为88.33 % ,显著高于单纯西药组的 42 .15 %、19.0 1%和 6 1.16 % (P <0 .0 1)。 (2 )中西医结合组复发率及激素不良反应发生率分别为 17.39%和 18.33 % ,明显低于单纯西药组的 6 8.6 3 %和 78.5 1% (P <0 .0 1)。结论

Objective:To investigate the management of primary nephrotic syndrome(PNS). Methods: 180 cases of PNS from 1995 to 2000 were analyzed. Results: (1) The complete remission rate, partial remission rate and total effective rate were 63.89%, 24.44% and 88.33%,respectively in the integrated traditional Chinese and Western medicine(TCM-WM), significantly higher than those(42.15%,19.01%and 61.16%)of control group with Western medicine alone(WM)( P<0.01);(2) The relapse rate and incidence of side effect were 17.39% and 18.33% in TCM-WM, significantly lower than those (68.63% and 78.15%)of control(P<0.01). Conclusion: TCM-WM is superior to WM alone in treating primary nephrotic syndrome.