盘花垂头菊倍半萜和酚类化合物结构的研究

Sesquiterpenes and Phenolic Compounds from Cremanthodium Discoideum

从盘花垂头菊全草分离出 10个化合物 ,经 IR,1H NMR,13 C NMR,DEPT,FABMS,EIMS等光谱方法分别鉴定为 :1β ,8-二当归酰氧基 - 2β -乙酰氧基 - 3β -羟基 - 4α -氯 - 10 ,11-环氧 -没药 - 7(14) -烯 (1) ;化合物 1的异构体 (2 ) ,对羟基苯甲酸 ,2 - (2′-正十九酰基 ) -苯乙基酯 (3a) ;对羟基苯甲酸 ,2 - (2′-正二十一酰基 ) -苯乙基酯 (3b) ;对羟基苯甲醛 (4) ;对羟基苯乙酮 (5 ) ;苯甲酸 (6 ) ;4 -羟基 - 3,5 -二甲氧基苯甲醛 (又称丁香醛 ) (7) ;7-甲氧基 - 6 -羟基香豆素 (又称异东莨菪素 ) (8) ;乌苏酸 (9) .其中 1,2 ,3a和 3b是新化合物 ,其它化合物 (4～ 9)是首次从该属植物中分到的 .

Ten compounds were isolated from the whole plant of Cremanthodium discoideum. On the basis of spectroscopic methods (IR, FABMS, EIMS, 1H NMR, 13 C NMR, DEPT), their structures were elucidated as 2β acetoxy 4α chloro 1β,8β diangeloyloxy 3β hydroxy 10,11 epoxybisabol 7(14) ene (1), an isomeride (2) of compound 1, p hydroxybenzoic acid, 2 (2′ nonadecanoyl) phenethyl ester (3a), p hydroxybenzoic acid, 2 (2′ heneicoscanoyl) phenethyl ester (3b), p hydroxybenzaldehyde (4), p hydroxyacetophenone (5), benzoic acid (6), 4 hydroxy 3,5 dimethoxybenzaldehyde (syringaldehyde) (7), 7 methoxy 6 hydroxy coumarin (scopoletin) (8), and ursolic acid (9).