老年终末期肾病合并贫血的临床研究

Clinical Study on the Elderly with End-stage Renal Disease with Anemia

目的:研究透析和促红细胞生成素等综合治疗终末期肾病合并贫血的效果。方法:对37例(60～78岁)终末期肾病合并贫血的患者,进行了前瞻性的治疗研究,应用透析、罗可曼(原名生血素、rHuEPO-β)、最初剂量50～120IU/kg体重,每周2次或3次皮下注射,2周后参考疗效调整剂量。结果:经过rHuEPO-β治疗后患者病情明显好转,食欲普遍增进,体力增强,血象均显著升高,不需再输血,未见过敏等不良反应。结论:透析与罗可曼等综合治疗终末期肾病合并贫血,能取得满意的疗效。

Objective: To study the result of dialysis and Recormon (rHuEPO-β) comprehensive treatment for the elderly widi end-stage renal disease (ESRU) with anemia.Methods: A prospective observational study was conducted.Thirty-seven patients, aged from 60 to 78 were investigated.The initial dosage(rHuEPO-β)was 50- 120 IU/kg, two or three times a week and adjusted according to the therapeutic effect. Recommendation regarding type of dialysis must be individualized. Results: After rHuEPO-β treatment, blood transfusion was not needed for any of the patients. Results showed that RBC, Hb and Hct were improved apparently. Conclusion; Appropriate dialysis and Recormon (rHuEPO-β) comprehensive treatment show a relatively good therapeutic effect for elderly with end-stage renal disease with anemia.