摘要
目的 提取分离板蓝根化学成分。方法 板蓝根用 95 %乙醇渗漉 ,用不同极性溶剂分级萃取 ,再分别用硅胶和大孔树脂作柱层析分离 ,测定纯化合物的理化常数和波谱数据 ,鉴定化学结构。结果 从板蓝根中分得 2个化合物 ,分别命名为依靛蓝双酮 (isaindigotidione, ) ,(E) -二甲氧羟苄吲哚酮〔(E) - 3- (3′,5′- dimethoxy- 4′- hydroxy-benzylidene) - 2 - indolinone, 〕。结论 和 为
Object To extract and separate the chemical constituents from the root of Isatis indigotica Fort (Cruciferae) Methods The root of I. indigotica was percolated with 95% ethyl alcohol, partitioned in solvents of different polarities and finally isolated on silica gel and macroporous resin columns The purified compounds obtained were identified and structurally elucidated by their physicochemical properties and spectral analysis Results Two compounds were obtained and named as isaindigotidione (Ⅰ) and (E)-3-(3′, 5′-dimethoxy-4′-hydroxybenzylidene)-2-indolinone Conclusion The two compounds were new
出处
《中草药》
CAS
CSCD
北大核心
2001年第12期1057-1060,共4页
Chinese Traditional and Herbal Drugs
基金
国家自然科学基金资助课题 ( No39170 877)
卫生部科学研究基金课题 ( No98-2 -110 )
关键词
板蓝根
依靛蓝双酮
(E)-二甲氧羟苄吲哚酮
中药
化学成分
the root of Isatis indigotica Fort
extraction and separation
isaindigotidione
(E)-3-(3′, 5′-dimethoxy-4′-hydroxybenzylidene)-2-indolinone