一株产生苝醌类化合物的真菌的化学成分研究(Ⅰ)

Studies on chemical constituents of fungus producing perylenequinones Ⅰ

目的 研究菌寄生菌属真菌 (Hypomyces sp.)菌丝体的化学成分。方法 用丙酮提取 ,硅胶柱分离纯化 ,化学和波谱学方法进行结构鉴定。结果 从菌丝体中分得 5个化合物 ,分别鉴定为 :竹红菌甲素 ( ) ,竹红菌丙素( ) ,痂囊腔菌素 C( ) ,1-吩嗪羧酸 ( )和 1,8-二羟基 - 9,10 -蒽醌 ( )。结论 化合物 ～ 为首次从该菌中分得。

Object To study the chemical constituents in the mycelia of Hypomyces sp Methods The mycelia were extracted with acetone and the chemical constituents of the extract were isolated and purified on silica gel column Chemical and spectral methods were used to determine the structures of the isolated compounds Results Five compounds were obtained and identified as: hypocrellin A (Ⅰ),hypocrellin C (Ⅱ), elsinochrome C (Ⅲ), 1 phenazinecarboxylic acid (Ⅳ), and 1,8 dihydroxy 9,10 anthraquinone (Ⅴ) Conclusion Compounds Ⅱ～Ⅴ were obtained from the mycelia of Hypomyces sp for the first time