双胎妊娠合并贫血与妊娠结局的分析

Analysis of effects of twin pregnancy with anemia on pregnancy outcome

目的 探讨双胎妊娠合并贫血对妊娠结局的影响。方法 将 4 96例双胎妊娠分为两组 ,妊娠合并贫血者 (贫血组 )共 3 2 1例 ,其余 175例为对照组 ,对两组病例的妊高征、产前出血、产后出血、早产、胎膜早破发生率与平均孕周、平均出生体重分别进行对照分析。结果 贫血组妊高征、产后出血、早产、胎膜早破发生率显著高于对照组 (P <0 0 5 ) ,且贫血严重程度与妊高征、产后出血发生率呈正相关 (P <0 0 5 ) ,与平均孕周呈负相关 (P<0 0 5 )。两组新生儿平均出生体重无显著差异 (P >0 0 5 ) ,但重度贫血病例的新生儿平均出生体重与对照组比较 ,有显著性差异 (P <0 0 5 )。结论 双胎妊娠合并贫血时各种并发症发生率成倍增加 ,特别是重度贫血对孕产妇和围生儿有严重的威胁。

Objective To determine the effect of twin pregnancy complicated anemia on pregnancy outcome.Methods 496 twin pregnancies were distributed to the anemia group with 321 gravidas and the control group with 175 gravidas.The incidence of pregnancy induced hypertension syndrome, antepartum hemorrhage, postpartum hemorrhage, premature birth,premature rupture of membranes, average gestational weeks and average neonatal birth weight were analyzed in these two groups respectively.Results The incidence of pregnancy induced hypertension syndrome, postpartum hemorrhage,premature birth, premature rupture of membranes in the anemia group were significantly higher than those in the control group(P<0 05). The degree of anemia was positively associated with pregnancy induced hypertension syndrome and postpartum hemorrhage(P>0 05). Negative correlation was found between the degree of anemia and the average gestational weeks(P<0 05). There was no significant difference in the average neonatal birth weight in two groups(P>0 05), but significantly decreased birth weight was found more in anemia gravidas compared with those in the control group(P<0 05).Conclusion When twin pregnancy complicated with anemia,the rate of the pregnancy complications are time high and the severe anemia is associated with greater risks for both mothers and fetuses.