牙髓炎中的细菌内毒素检测及与临床症状的关系

Assay the LPS in pulpitis and research the relationship between LPS and pulpitis

目的 研究急、慢性牙髓炎症状态下牙髓腔中的细菌内毒素含量及细菌内毒素含量与临床症状间的关系。方法 采用鲎试剂显色技术 ,定量检测急、慢性牙髓炎症状态下的牙髓腔内细菌内毒素含量 ,与正常组进行比较 ,分析内毒素含量与牙髓炎症状态下的临床表现间的关系。结果 急、慢性牙髓炎组的内毒素含量有极大差异 ,前者明显高于后者 ,且具有极显著统计学意义。两者与正常对照组相比 ,也有极显著统计学意义 ,均明显高于正常对照组。结论 内毒素含量与临床表现中的自发痛。

Objective To stuby the amounts of LPS in acute pulpitis and chronic pulpitis in existenc of LPS in pulpitis and to Analyse the relation between the amounts of LPS in pulpitis and the clinical symptoms. Methods The methods of LAL test were used to analyze the amounts of LPS in the root canal of pulpitis,unler the condition of actual pulpitis and chronic pulpitis. Results The amoumts of LPS in 23 acute pulpitis were found significently higher than that in 22 chronic pulpitis, P <0 0001;The amounts of LPS in acute or chronic pulpitis were significently higher than those in the normal control, P <0 0001;The mean value of actue pulpitis was 9 34±0 73μgml; the chronic pulpitis was 4 45±0 85μgml,the normal control was 0 018±0 004mgml.Conclusion The results also showed that the exudate,radialpain had the closest relationship with the amounts of LPS.