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染色体易位携带者的胚胎植入前遗传学诊断研究进展 被引量：3

Advances in preimplantation genetic diagnosis for chromosomal translocation carrier
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摘要 染色体易位是常见的染色体结构异常。应用荧光原位杂交技术 ,染色体易位携带者可在胚胎植入前遗传学诊断的帮助下增加正常妊娠的机会。现就相互易位减数分裂的情况进行综述 ,并讨论应用荧光原位杂交技术对染色体易位携带者进行胚胎植入前遗传学诊断的策略。 Chromosomal translocation is a kind of common chromosomal abnormality. The carriers with chromosomal translocation could have more chance of normal pregnancy with the help of fluorescence in situ hybridization (FISH). This is a review aimed at analyzing the meiosis types of the translocation chromosome. The strategy of preimplantation genetic diagnosis for the carriers with chromosomal translocation is also discussed.
作者 谭跃球 卢光琇 李麓芸
机构地区 中南大学湘雅医学院人类生殖工程研究室
出处 《中华医学遗传学杂志》 EI CAS CSCD 2002年第1期76-78,共3页 Chinese Journal of Medical Genetics
基金 国家自然科学青年基金 (391 0 0 0 60 ) 湖南省自然科学基金 (1 0 1 3- 8) 湖南省医药卫生基金 (0 0 0 2 )~~
关键词 染色体易位 荧光原位杂交 胚胎植入前遗传学诊断 chromosomal translocation fluorescence in situ hybridization preimplantation genetic diagnosis
分类号 R394-33 [医药卫生—医学遗传学]
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参考文献24

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共引文献7

同被引文献13

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中华医学遗传学杂志
2002年 第1期

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