月经初潮早晚对女大学生骨骼生长发育与骨量的影响

Effect of the Age of Menarche on Bone Development and Bone Mass in College Students

目的：探讨月经初潮早晚对女大学生骨骼生长发育与骨量的影响。方法：以５５名女大学生为研究对象，测量身高、骨密度（ＢＭＤ）、骨宽等指标。结果：月经初潮早晚对身高、尺骨宽、桡骨宽影响较小，而尺骨ＢＭＤ、桡骨ＢＭＤ随着月经初潮年龄的逐渐增长大致呈依次递减的规律，并且组间比较呈显著性差异（Ｐ＜０．０５或Ｐ＜０．０１）。结论：月经初潮早晚对女大学生骨骼发育与骨量有一定的影响，表现为月经初潮早的学生比月经初潮晚的学生骨形成活动更活跃，积累了更多的骨矿物质，这主要是由于月经初潮早晚对女性体内性激素水平有影响，而性激素水平又直接影响骨代谢活动。

Objective To investigate the effect of the age of menarche on bone shape and bone mass in female college students in Northern Jiaotong University. Methods Fifty-five female college students were chosen as our subjects. The height, hone mineral density (BMD) and bone width of these students were measured. Results Menarche has little effect on height and bone width, but ulna and radius BMD decreases with the increasing of the age of menarche. Moreover, there is significant difference in BMD between age groups. Conclusion Menarche has some effects on bone development and bone mass. The bone formation is more active in students who has early menarche, and more bone mass is accumulated due to the age of menarche affecting the level of sex hormone that directly affect hone metabolism in adolescent students.