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阻塞性睡眠呼吸暂停血压升高的机制 被引量:3

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摘要 阻塞性睡眠呼吸暂停(OSA)引起血压增高的机制可能与低氧血症、高碳酸血症、唤醒反应等所致的交感神经活动改变,体液因子,压力反射异常,血管重塑,内皮功能异常,遗传和年龄等因素共同参与有关。
出处 《国外医学(内科学分册)》 2002年第1期1-3,14,共4页 Foreign Medical Sciences(Section of Internal Medicine)
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同被引文献28

  • 1范洁,郭兮恒,于桂芝,钟儒德,张惠楠,黄席珍.阻塞性睡眠呼吸暂停综合征与高血压病──附240例监测报告[J].中华心血管病杂志,1995,23(5):345-347. 被引量:16
  • 2Xie P, McDowell TS, Chapleau MW, et al . Rapid batoreceptor resetting in ch tonic hypertension implications for normalization of arterial pressure [ J]. Hypertension, 1991 ;5 (2) :72-9.
  • 3Maillard D, Fineyre F, Dreyfuss D, et al. Pressure-heart rate responses to alpha-adrenergic stimulation and hormonal regulation in normotensive patient s with obstructive sleep apnea [J]. Am J Hypertens, 1997; 10(1): 24-31.
  • 4Fletcher EC, Lesske J, Qain W, et al . Repetitive, episodic hypoxia causes diurnal elevation of blood pressure in rats[J]. Hypertension,1992;19(6 Pt 1) :555-61.
  • 5Bao G, Metreveli N, Li R,et al. Blood pressure response to chronic episodic hypoxia: role of the sympathetic nervous system [ J ].J Appl Physiol,1997, 83(1): 95-101,.
  • 6Phillips BG, Narkiewicz K, Pesek CA, et al. Effects of obstructive sleep apnea on endothelin- 1 and blood pressure[J] .J Hypertens,1999 Jan,17(1) :61.
  • 7Narkiewicz K, Pesek CA, Kato M, et al. Baroreflex control of sympathetic nerve activity and heart rate in obstructive sleep apnea [J].Hypertension,1998 Dec,32(6):1039.
  • 8Fletcher EC. The relationship between systemic hypertension and obstructive sleep apnea: facts and theory[J]. Am J Med, 1995 Feb,98(2):118.
  • 9Fletcher EC, Lesske J, Qain W, et al. Repetitive, episodic hypoxia causes diurnal elevation of blood pressure in rats[ J ] . Hypertension,1992 Jun,19(6 Pt1) :555.
  • 10Bao G, Metreveli N, Li R, et al. Blood pressure response to chronic episodic hypoxia: role of the sympathetic nervous system[ J ]. J Appl Physiol,1997 Jul,83(1) :95.

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