维奥欣治疗冠心病心绞痛56例疗效观察(附消心痛30例)

The Effect Observation of Weiaoxin in Treating Coronary Heart Disease and Angina Pectoris in 56 Cases

目的:观察维奥欣抗心绞痛疗效,改善缺血性心电图及降脂作用。方法:治疗组(维奥欣组)56例,男34例,女22例,年龄58±5岁,给维奥欣160mg/次,1日3次,疗程6周;消心痛组30例,男性17例,女性13例,年龄57±6岁,给消心痛10mg/次,1日3次,疗程6周。结果:①治疗组抗心绞痛显效率51.8%,对照组53.3％(P>0.05)。②治疗组心电图改善总有效率35.7％,对照组36.7(P>0.05)。③治疗组降低血胆固醇(TC)和甘油三酯(TG)的总有效率为82.9％和80.6％;消心痛组分别为14.6％和15.4％。④维奥欣无任何毒副作用,临床使用安全。结论:维奥欣在抗心绞痛,改善缺血性心电图方面与消心痛相似,但维奥欣是一个安全、有效的降脂药物,特别适用于高脂血症合并冠心病的治疗。

To observe the efficacy of weiaoxin for angina Pectoris, and also the action of it for improving ischemic EGG and reducing lipoid.Method: treatment group(weiaoxin group)56 patients,M34,F22(58+ 5)were treated with weiaoxin in a dose of 160mg t. i. d for 6 weeks and comparison group(Isosorbide dinitrate tablets group) :30 patients M17, F13(57 + 6 ) were treated with Isosorbide dinitrate tablets in a dose of 10mg t.i.d for 6 weeks, too. Result:1 As the comparison result showed that the effective rate in the treatment group was 51.8% .and the comparison group was 53.3%(P>0.05).2the ECG effective rate in the treatment group showed 35.7% . and comparison group was 36.7%(P>0.05); 3The total effective rate of the treatment group in reducing Cholesterol (Tc) and hyperglyceridemia (TG) was 82.9% and 80.6%, Isosorbide dinitrate tablets group was 14.6% and 15.4% ;4 There is no adverse reactions found in weiaoxin.So it is a safe drug for medication Conclusion: :There is something similar between weiaoxin and Isosorbide dinitrate tablets in antagonizing angina pectoris and in improving ischemic ECG. but the most important thing is that weiaoxin is a kind of safe, effective lipoid-reducing medicine, it is especially fit for the treatment of hyper-lipoidemia with coronary heart disease.