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大肠杆菌对氟喹诺酮类药物的耐药机制研究现状 被引量:13

The study status quo on mechanisms of fluoroquinolone resistance in Escherichia coli
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摘要 大肠杆菌是典型的革兰氏阴性杆菌 ,其耐药谱广 ,耐药机制复杂 ,是国内外耐药性研究较为详细的细菌。大肠杆菌对氟喹诺酮药物的耐药性问题是当前国内外研究的热点。本文就大肠杆菌与氟喹诺酮耐药性有关的 gyrA、gyrB、parC、parE点突变 ;多药外输泵 ;多重耐药基因 ;抗性质粒等方面的研究进展作一综述。
出处 《中国兽药杂志》 2002年第2期49-53,共5页 Chinese Journal of Veterinary Drug
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