摘要
脑 PET显像是利用正电子示踪剂检测脑血流量 ,血容量 ,局部葡萄糖利用率 ,氧、氨基酸代谢和血脑屏障的完整性 ,以及受体的位置、密度和分布等。因此 ,PET不仅能研究各种脑疾病的过程和特征 ,评价神经系统疾病治疗效果 ,而且能研究正常脑功能。
Positron emission tomography (PET) with positfon emitting tracers can provide the biochemical information which is obtained from the measurement of cerebral blood volume (rCBV),regional cerebral blood flow (rCBF) and/or integrality of the blood brain barrier, regional cerebral glucose utilize rate, oxygen extraction fraction (OEF) and cerebral metabolic rate of oxygen (rCMRO 2), and of amino acids (rCMRaa), and the site, density and distribution of the receptors. Thus,PET imaging can investigate the physiochemical process and characteristic of brain diseases and consequently insights concerning the evaluation of disease states, response to therapy, and prognostic indicators.
出处
《国外医学（放射医学核医学分册）》
2001年第6期246-249,共4页
Foreign Medical Sciences(Section of Radiation Medicine and Nuclear Medicine)
关键词
正电子放射性药物
正电子发射断层显像
脑功能
PET代谢示踪剂
cerebral blood volume
regional cerebral blood flow
metabolism
receptor
positron emitting tracer
positron emission tomography
brain
