摘要
纤溶酶原激活剂 (plasminogen activator,PA)是一种特异性的蛋白水解酶 ,它能将无活性的酶前体转变为纤溶酶 (plasmin)。纤溶酶是一种有效的非特异性的蛋白水解酶 ,能够裂解血液内的纤维蛋白凝块使其成为可溶性的多肽。本文描述了纤港酶原激活系统的一些生化特征 ,及对纤溶酶原激活剂活性的测定方法。纤溶酶原激活剂在血栓性疾病和出血性疾病的诊断具有潜在应用价值。
Plasminogen activators (PA) are specific proteolytic enzymes Which convert the inactive proenzymen to plasmin.The plasmin formed is a potent and nonpecific protease which cleaves blood fabrin clots into soluble polypeplide. This article describes some biochemical chatacteristic of the different compotents of the plsminogen activator system,current methods for assay of the activity of the PA.The potential application of PA as diagnostic tools in diseases of the thrombi.
出处
《国外医学（放射医学核医学分册）》
2001年第6期262-264,共3页
Foreign Medical Sciences(Section of Radiation Medicine and Nuclear Medicine)
