肝癌治疗与微创外科观念

CONCEPT OF MINIMALLY INVASIVE SURGERY AND TREATMENT OF PRIMARY LIVER CANCER

Surgical oncology has progressed from regional cancer therapy to curative resection during the period from 19th to 20th centuries. Based on the recent advances in early diagnosis of solid tumors, minimally invasive surgery with organ preservation has attracted more attention. Hepatic cancer surgery has also progressed from lobectomy of large liver cancer in the 1950s to limited resection of small liver cancer in the 1970s, which reflected the influence of "concept of minimally invasive surgery". In the recent years, regional cancer therapies for liver cancer develop rapidly, and it is considered as an extension of this "concept". It is predicted that this "concept" will further influence the pattern of liver cancer treatment. However, the implication of this "concept" on cancer treatment will be limited by the biological characteristics of cancer cells. Multimodality combination treatment, biotherapy and studies on metastatic recurrence will probably the key issues to further enhance this "concept" on cancer treatment.