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阿尔采木病分子遗传学研究进展 被引量:1

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摘要 淀粉样前体蛋白 (APP)、早老素 - 1(PS- 1)和早老素 - 2基因突变引起的早发家族性阿尔采木病非常少见 ,Apo Eε4等位基因与近半数的晚发 AD有关联 ,其它一些基因虽有研究 ,但结果却不肯定。PS- 1缺失可引起 APP水解代谢紊乱 ,导致 APP在神经元中沉积。
作者 唐牟尼
出处 《国外医学(精神病学分册)》 2001年第3期181-184,共4页 Foreign Medical Sciences(Section of Psychiatry)
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  • 1王鸣鹏,中华放射学杂志,1996年,30卷,373页
  • 2贾辅忠,临床肝胆疾病,1984年,18页

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