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醛固酮受体拮抗剂与心力衰竭 被引量:6

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摘要 八十年代后期确定人心脏细胞内有醛固酮(ALD)受体,对人心肌有直接的、选择性的ALD作用[1].人心肌细胞、内皮细胞和间质细胞(成纤维细胞)均有ALD受体表达.盐皮质激素受体(MRs)对ALD和糖皮质激素(GC)有相同的亲和力,而血中GC与ALD之比为100:1,因此MRs常被GC所占据.
作者 戴闺柱
出处 《中国医药导刊》 2001年第4期274-274,F003,共2页 Chinese Journal of Medicinal Guide
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