Amplatzer蘑菇伞器治疗小儿动脉导管未闭的临床应用

Clinical evaluation of the Amplatzer ductal occluder in the treatment of patent ductus arteriosus in children

目的 :探讨应用 Am platzer蘑菇伞器治疗小儿动脉导管未闭 ( PDA)的临床疗效及价值。方法 :本组共 68例 ,年龄 8个月～ 12岁 (平均 6.4岁 ) ,体重 6.5～ 3 0 (平均 18.2 ) kg,PDA直径为 3～ 8mm ,术中行右心导管检查取血 ,测压 ,术后 5～ 15 m in行降主动脉造影 ,测肺动脉压 ,主动脉压。术后 1月 ,3月 ,6月分别行 X线及超声心动图检查 ,了解有无残余分流及封堵器位置。结果 :本组 68例均应用 Am platzer PDA磨菇伞器治疗 ,成功率 10 0 % ,疗效满意 ,无并发症 ,术后 3 d行超声心动图检查显示无 1例分流。结论 :应用 Amplatzer蘑菇伞器治疗 PDA创伤小 ,操作简单 ,使用广泛 ,成功率高 。

AIM To assess the safety and efficacy of the Amplatzer ductal occluder in the treatment of patent ductus arteriosus(PDA) in children. METHODS: A total of 68 patients underwent transcatheter occlusion of PDA at a median age of 6.4 years (range 8 month^12 years) and at a median weight 18.2 kg (range 6.5~30 kg). The diameters of ductus arteriosus were 3~8 mm. Aorta and pulmonary pressures were measured during and post implantation, and descending aorta imaging was performed 5~15 min post implantation. X ray and 2D echocardiogram examinations were performed 1,3 and 6 months after implantations to reveal the shunt and devices position. RESULTS: Complete closure was achieved in all patients (100% closure rate) and no complications were observed. No residual shunt was found 1 month after implantation by 2D echocardiogram. CONCLUSION:Transcatheter occlusion of PDA using Amplatzer ductal occluder is safe,effective and easy to perform. It is a satisfactory alternative method in the treatment of PDA in children.