经皮球囊肺动脉瓣成形术133例

Percutaneous balloon pulmonary valvuloplasty in 133 patients

目的 :评价经皮球囊肺动脉瓣成形术 ( PBPV)治疗肺动脉瓣狭窄 ( PS)的临床疗效和安全性。方法 :1989～ 2 0 0 0年 PBPV患者共 13 3例 ,年龄 1～ 5 7( 12± 10 )岁。结果 :PBPV术后即刻右室收缩压由 97± 3 5 mm Hg降至 5 2± 2 0mm Hg,肺动脉至右心室跨瓣压差由 67± 3 6m m Hg降至 12± 11m m Hg( P<0 .0 1)。 2 8例发生右室流出道痉挛 ,2例患者行外科手术治疗 ,余者口服普萘洛尔 3～ 6个月。超声随访 6个月～ 8年 ,右室一肺动脉收缩压差明显下降。结论 :PBPV操作安全 ,疗效可靠 ,可作为治疗各年龄组

AIM:To evaluate the safety and effectiveness of percuteneous balloon pulmonary valvuloplasty(PBPV) for pulmonary valve stenosis(PS). METHODS:From March 1989 to November 2000,133 patients of age 12±10(ranged from 1~57) years were studied. RESULTS:Right ventrical systolic pressure decreased from 97±35 to 52±20 mm Hg and systolic pressure gradient across the pulmonary valve decreased from 67±36 to 12±11 mm Hg( P <0.01) immediately after PBPV. Twenty eight patients developed reactive infundibular spasm,2 of them underwent surgical operation,the other were treated with propranolol for 3~6 months. Follfowed up 0.5~8 years by echocardiography,their systolic pressure gradient between right ventricle and pulmonary artery decreased significantly. CONCLUSION:PBPV is a safe and effective method,which is the first choice for patients of any age groups.