摘要
目的:探讨EBV-DNA 检查在不典型传染性单核细胞增多症中的应用价值,指导临床合理治疗。方法:取 16例急性扁桃体炎,14例典型传染性单核细胞增多症,6例不典型传染性单核细胞增多症外周血标本,用 PCR法检测 EBV-DNA。结果:20例传染性单核细胞增多症,EBV-DNA阳性17例,其中典型传染性单核细胞增多症阳性率达 78.5％,不典型传染性单核细胞增多症阳性率高达100％,而急性扁桃体炎16例,阳性率仅25％。结论:PCH法检测EBV-DNA对儿童传染性单核细胞增多症的诊断起确诊作用,且可帮助医生更好认识不典型传染性单核细胞增多症,有利确定临床治疗方案。
Objective: Assess the clinical value for detecting EBV-DNA in nontypical infectiousmononucleosis in children. Methods: The EBV-polymerase chain reaction was used for detecting EBV in20 infectious mononucleosis and 16 acute tonsillitis. Results: The positive rate of EBV-DNA in typical infectious mononucleosis and nontypical infectious mononucleosis was 75% and 100% separately muchhigher than that of acute tonsillitis (25%). Conclusion: The EBV-DNA detection has diagnostic value inchildren infectious mononucleosis, especially for nontypical infectious mononucleosis. It is also useful forevaluating treatment.
