期刊文献+

鞘内注射甲氨蝶呤和地塞米松治疗狼疮脑病的临床观察 被引量:3

Clinical observation of encephalopathy of systemic lupus erythematosus with intrathecal methotrexate and dexamethasone
下载PDF
导出
摘要 目的:探讨鞘内注射甲氨蝶呤和地塞米松治疗狼疮脑病的疗效。方法:选择14例住院的系统性红斑狼疮病人,临床上具有精神和神经异常表现,脑脊液检查、头颅CT 异常表现的狼疮脑病,在常规剂量糖皮质激素治疗狼疮脑病不能缓解的情况下鞘内注射甲氨蝶呤和地塞米松。结果:14例病人都得到了不同程度的缓解 结果:鞘内注射甲氨蝶呤和地塞米松是治疗狼疮脑病的一种安全而有效的方法,值得进一步的临床研究。 Objective: The effect of intrathecal injections with methotrexate and dexamethasone wasassessed on encephalopathy of systemic lupus erythematosus (CNS-SLE). Methods: Intrathecal injec- tions with methotrexate and dexamethasone were administered to 14 inpatients with CNS-SLE, of whichCNS-SLE was diagnosed through abnormal psychonervous manifestations, cerebrospinal fluild test and CTof head and of which CNS-SLE could not be improved with routine dose of glucocorticoid. Results: Four-teen patients with different CNS-SLE manifestations attained a good response after therapy with intrathecalinjections with methotrexate and dexamethasone. Conclusion: This clinical observation shows that in-trathecal injections with methotrexate and dexamethasone appear to be safe and effective for the manage-ment of CNS-SLE. This therapy should be studied continuously.
出处 《医学科技》 2001年第4期23-25,共3页
关键词 系统性红斑狼疮 中枢神经系统疾病 鞘内注射 甲氨喋呤 地塞米松 Systemic lupus erythematosus Central nervous system disease Intrathecal injections
  • 相关文献

参考文献3

共引文献52

同被引文献28

引证文献3

二级引证文献6

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部