血府逐瘀汤治疗肾移植术后红细胞增多症20例疗效观察

Treatment of Erythromatosis After Renal Transplantation by Xuefu Zhuyu Tang: A Clinical Observation of 20 Cases

目的：观察血府逐瘀汤对肾移植术后红细胞增多症（ＰＴＦ：）的疗效。方法：将３５例ＰＴＥ病人随机分为中药组（２０例），对照组（１５例）。采用前瞻性研究，中药组予血府逐瘀汤治疗，对照组予洛汀新治疗。观察临床疗效、外周血 ＲＢＣ、Ｈｂ、Ｈｃｔ、ＢＰＣ值及全血粘滞度等的变化。结果：２组疗效差异无显著性意义，对ＲＢＣ、Ｈｂ、Ｈｃｔ值及全血粘滞度的影响差异亦无显著性意义，中药组 ＢＰＣ 下降较对照组明显，差异有显著性意义；对血压等无影响。结论：血府逐瘀汤在改善肾移植术后高粘状态方面与ＡＣＥＩ类药功效类同，是治疗肾移植术后红细胞增多症的有效方剂。

Objective: To observe the curative effect of Xuefu Zhuyu Tang (XZT) for erythromatosis after re- nal transplantation. Methods: 35 cases were allocated to herbal medicine group (20 cases) and control group (15 cases) randomly. The herbal medicine group was treated by XZT and the control group by lotensin, and the value of RBC, Hb, Hct and BPC and whole blood viscosity of the peripheral blood were observed. Results: These was no significant difference of clinical effect between two groups, the value of RBC, Hb, Hct and whole blood vis- cosity also showed no significant difference, while the re- duction of BPC value in herbal medicine group was markedly different from that of control group. Blood pres- sure was not affected. Conclusion: Similar to ACEI, XZT can reduce the high blood viscosity after renal transplan-tation, and is an effective remedy for such cases.