膳食补充剂对受医疗辐射人员慢性疲劳症的防护干预

Effect of protectin intervention of functional food on radiologist with obvious chronic fatigue syndrome

目的使用膳食补充剂抗疲劳Ⅰ号胶囊干预介入放射诊疗人员防护前后的T细胞亚群(T-sub)IL-2R(CD25)NK细胞(CD16)的影响。方法在32例放射科人员中选择从事介入诊疗10年以上,慢性疲劳症状突出者10例为观察对象;设防护前组(BG)、防护后组(AG)、对照组(CG),使用流式细胞仪测定防护前后的T-subCD25CD16。结果AG与BG相比,总T细胞CD3上升,亚群中的CD8呈上升,CD4略有下降,CD4/CD8下降,CD25和CD16上升(P<0.05,0.01);BG与CG相比,CD3、CD4、CD8、CD16、CD25均呈低下水平(P<0.05,0.01),CD4/CD8比值出现异常升高等。结论长期从事医疗辐射环境在危害机体造血的同时,也危害T-subCD16CD25的表达水平,I号胶囊有明显的改善造血、调节细胞免疫功能的抗辐射作用。

Objective To observe medical radiation environment effect on radiologists'sub T,IL 2R(CD25),NK(CD16)cells before and after their taking antifatigue capsule Ⅰ for protection.Method To pick up 10 objects out of 32 radiologists who have been engaged over ten years on radioisotope diagnosis and show obvious chronic fatigue syndrome.Next to divide them into group before protection(BG),group after protection(AG) and control group(CG).Then to determine their sub T,IL 2R and NK cells with FACS.Result Compared with BG,AG indicates the growing number in CD3 of T cells,in CD8 of sub T cells,while the number of CD4 decreases slightly,that of CD4/CD8 falls,and that of CD25 and CD16 rises with statistical significance(P< 0.05,0.01).Compared with CG,BG shows the small number in CD3,CD4,CD8,CD16 and CD25(P< 0.05,0.01),while the specific value of CD4/CD8 appears abnormal rising etc.Conclusion Medical radiation environment will damage hemopoietic organ with the expression of sub T cells,CD25 and CD16 cells.Antifatigue capsule Ⅰ has good effect of radioresistance and can improve the cell immunocompetence.