口腔白斑和扁平苔藓中TSGF的检测

Detection of TSGF in oral leukoplaida and lichen planus

目的 探讨恶性肿瘤特异性生长因子 (TSGF)的检测对口腔白斑和扁平苔藓的临床意义。方法 对 45例鳞癌 ,12例白斑和 3 2例扁平苔藓患者 ,测定其血中TSGF的浓度。结果 鳞癌的阳性率为 5 3 .3 3 % ,白斑为3 3 .3 3 % ,扁平苔藓为 2 5 .0 0 %。白斑与鳞癌的阳性率无显著性差异 (P >0 .0 5 ) ,扁平苔藓与鳞癌的阳性率有显著性的差异 (P <0 .0 5 )。

Objective To investigate the clinical significance of tumor specific growth factor(TSGF) in oral leukoplakia(LK) and lichen planus(LP). Methods TSGF consistency was examined in 45 cases of oral squamous cell carcinomas(CSCC).12 cases of LK,32 cases of LP. Results Positive rate of SCC was 55.33 %,LK was 33.33 %,LP was 25%.Positive rate of SCC was not significantly higher than that of LK( P > 0.05 ).Positive rate of SCC was significantly higher than that of LP( P < 0.05 ). Conclusions Examining TSGF is regarded as a primal means in predicting malignant potential of oral mucosal diseases.