摘要
目的 :探讨X综合征患者血清尿酸水平与卒中的关系。方法 :对按性别、年龄、糖尿病病程和血HbAlc水平配对的 2 0例有卒中史及 2 0例无卒中史的有X综合征的NIDDM病人、 2 0例单纯NIDDM病人和 2 0例正常人测定其血清尿酸水平并进行分析研究。结果 :单纯NIDDM病人的血清尿酸水平显著低于正常对照组 (P <0 0 5 ) ,其水平与血糖呈负相关 ;而有X综合征的病人血清尿酸水平显著高于单纯NIDDM病人 (P <0 0 1)及正常对照组 (P <0 0 5 ) ;而在有X综合征的病人中 ,有卒中史的血清尿酸水平显著高于无卒中史者 (P <0 0 5 )。同时血清尿酸水平与血清胰岛素及C肽水平之间存在相关。结论 :血清尿酸水平可能是X综合征患者卒中发病率的一个危险因子。
Objective: To obseve the serum uric acid lever and its relation to stroke in syndrome X Methods: The serum uric acid lever was measured in 20 syndorme X patients with history of stroke, 20 syndorme Xpatients without history of stroke, 20 simple NIDDM patients and 20 healthy subjects matched for age, sex, duration of diabetes and HbAlc lever Results: The serum uric acid lever was significantly lower in simple NIDDM patients than in normal subjects ( P <0 05) A negative correlation between serum uric acid and blood glucose was found in simple NIDDM patients The serum uric acid lever was significantly higher in syndrome X patients than in normal subjects ( P <0 05) and in simple NIDDM patients ( P <0 01), and also was significantly higher in syndrome X patients with history of stroke than in those without history of stroke ( P <0 05),furthermore, serum uric acid lever was significantly correlated with serum insulin and C peptide levers Conclusion: The serum uric acid lever maybe a risk factor of stroke in syndrome X
出处
《广州医药》
2002年第1期62-64,共3页
Guangzhou Medical Journal
