局部药物注射与口服药治疗三叉神经痛的疗效对比

The effective contrast of treating trigeminal neuralgia with injection and tablet

目的 :观察局部注射药物与口服药治疗三叉神经痛的疗效差异。方法 :选择门诊三叉神经痛的患者 ,并随机分成两组 ,即口服药物组给予卡马西平100mg1～2次 /天 ,若不能止痛每天增加100mg ,直到控制疼痛为止 ,将最小有效剂量作为维持量 ,一般为600～800mg/d ,共36例。局部药物注射组以4 %氟羟强的松龙0.5ml加2 %利多卡因1.5ml混合后准确地注射到罹患神经通过的骨孔处 ,共32例。结果 :口服药物组6个月有效27例 ,有效率75% ,局部药物注射组6个月有效30例 ,有效率94 %。结论 :局部药物注射组的疗效明显优于口服药物组。

Objective: To observe different effects of treating trigeminal neuralgia(TN)with injection and tablet.Methods: To choose patients who suffered from TN in out-patient department of the hospital and then they were divided into two groups at random.In one group the patients took carbamazepine tablets 100mg qd or bid ,if no effect to add 100mg every day until to control hurt,regarding the minimum dose as optimal dose,as usual,600～800mg every day,36 cases in all.In another group the patients were injected with mixed liquid of 4% triamcinolone 0.5 ml and 2% lidocaine 1.5ml into bony aperture which nerves go through,32 cases in all. Results:In taking tablets group,27 cases had effect during first 6 months,about 75%.In injecting group,30 cases had effect during first 6 months about 94%. Conclusion:The injecting treatment excels another one.