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银屑病易感基因研究进展 被引量:3

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摘要 银屑病是常见的一种多基因遗传病。迄今为止 ,在 OMIM中收录了 PSORS1、PSORS2、PSORS3、PSORS4、PSORS5、PSORS6、PSORS7共 7个银屑病易感基因位点。CDSN、S10 0 A7、TNF- α和 HCR等银屑病的候选基因研究也被广泛开展。
出处 《国外医学(遗传学分册)》 2001年第6期318-321,共4页 Foreign Medical Sciences(Section of Genetics )
基金 国家 8 63资助项目 (No.2 -19-0 1-0 4-0 4)
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  • 1C. Enerb?ck,S. Nilsson,F. Enlund,A. Inerot,L. Samuelsson,J. Wahlstr?m,G. Swanbeck,T. Martinsson. Stronger association with HLA-Cw6 than with corneodesmosin (S-gene) polymorphisms in Swedish psoriasis patients[J] 2000,Archives of Dermatological Research(11):525~530

同被引文献61

  • 1邵长庚.我国银屑病的流行和防治现状[J].中华皮肤科杂志,1996,29(2):75-76. 被引量:72
  • 2全国银屑病流行调查组.全国1984年银屑病流行调查报告[J].中华皮肤科杂志,1986,19:253-261.
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  • 5ander E, Kruglyak L. Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results. Nat Genet, 1995,11: 241-247.
  • 6Trembath RC, Clough RL, Rosbotham JL, et al. Identification of a major susceptibility locus on chromosome 6p and evidence for further disease loci revealed by a two stage genome-wide search in psoriasis. Hum Mol Genet, 1997, 6: 813-820.
  • 7Balendran N, Clough RL, Arguello JR, et al. Characterization of the major susceptibility region for psoriasis at chromosome 6p21.3. J Invest Dermatol, 1999, 113: 322-328.
  • 8Oka A, Tamiya G, Tomizawa M,et al.Association analysis using refined microsatellite markers localizes a susceptibility locus for psoriasis vulgaris within a 111 kb segment telomeric to the HLA-C gene. Hum Mol Genet, 1999, 8: 2165-2170.
  • 9Nair RP, Stuart P, Henseler T,et al. Localization of psoriasis-susceptibility locus PSORS1 to a 60-kb interval telomeric to HLA-C.Am J Hum Genet, 2000, 66: 1833-1844.
  • 10Zhang X, Wang H, Te-Shao H, et al. The genetic epidemiology of psoriasis vulgaris in Chinese Han. Int J Dermatol, 2002, 41:663-669.

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