民航飞行人员的血清抗氧化状态(英文)

Serum Antioxidant Status of Civil Aircrew

目的研究宇宙辐射对民航飞行人员血清抗氧化状态的影响 ,并为保健措施的设计提供生化依据。方法分析新疆民航累积飞行时数超过 40 0 0h的飞行人员 2 30人 ,新疆地面居民 37人及天津地面居民37人的血清总抗氧化能力 (TAOC) ,超氧化物歧化酶 (SOD)及脂质过氧化物降解终产物丙二醛 (MDA)含量 ,并比较 3组间血清抗氧化指标数据的差异。结果飞行组的 3项血清抗氧化指标都高于地面对照(TAOC :P <0 .0 0 1 ,SOD :P <0 .0 0 1 ,MDA :P <0 .0 0 5)。新疆地面组的TAOC及SOD皆高于天津地面组 (P值均 <0 .0 0 1 ) ,MDA则无差异。所测人群中的 3项血清抗氧化指标间呈正相关现象。结论民航飞行组的血清抗氧化状态反应出所受宇宙辐射损伤并未超出机体代偿能力 ,但已有较高的血清脂质过氧化反应 。

Objective To study the serum antioxidant status in civil aircrew members who had more than 4000 h of cumulative flight hours, therefore exposed to a higher dose of cosmic radiation comparing to the dose received by ground residents. Method Differences in the serum levels of total antioxidant capacity (TAOC), superoxide dismutase (SOD) and malondialdehyde (MDA) were investigated in 230 aircrew members, 37 local ground residents in Xinjiang ,and 37 ground residents in Tianjin. Result Significantly higher levels of all the three serum indexes were found in civil aircrew members. Serum levels of TAOC and SOD were higher in Xinjiang than in Tianjin ground residents, although no difference was found for MDA. Positive correlations were observed among the three serum indexes in this study. Conclusion The elevated serum level of MDA in civil aircrew members deserves a proper attention by the health care policy makers.