糖尿病肾病患者血浆t-PA、PAI变化的初步观察

Changes of Plasma t-PA,PAI in Diabetic Patients

检测25例糖尿病肾病患者血浆组织纤溶酶原激活物抗原(t-PA:Ag)和活性(t-PA:A)、纤溶酶原激活抑制物活性(PAI:A)以及血管性假血友病因子抗原(VWF:Ag)。结果表明,患者的t-PA:Ag低于正常,PAI:A,VWF:Ag高于正常,提示尿蛋白增多的糖尿病患者纤溶活性减低并可能伴血检形成。

Plasma t-PA:Ag, T-PA:A, PAI:A and VWF were detected in 25 cases of diabetes. The results showed that t-PA:Ag, t-PA:A were lower than mormal and PAI:A was higher than mormal control. VWF:Ag was also elevated. This indicates that fibrinolysis increases when excretion of urinary albumin is increased in diabetes. This change may indicate the possibility of thromosis.