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毛细管电泳及手性选择剂在手性药物分离中的应用 被引量:5

Chiral Separation of Drugs by Capillary Electrophoresis
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摘要 手性药物的毛细管电泳拆分技术发展迅速 ,综述毛细管电泳法拆分手性药物的机理、方法及应用 ,并重点介绍近年来各类手性选择剂的开发现状。 The recent progress in chiral drug separation by capillary electrophoresis was reviewed, including the theory, methods and applications of chiral separation. Especially, the development of chiral selectors in recent years was introduced.
作者 赵霞 刘文英
出处 《药学进展》 CAS 2001年第6期344-348,共5页 Progress in Pharmaceutical Sciences
关键词 毛细管电泳 手性选择剂 手性药物 手性拆分 分离 Capillary electrophoresis Chiral selector Chiral drug Chiral separation
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  • 1Y. Tanaka,S. Terabe. Separation of the enantiomers of basic drugs by affinity capillary electrophoresis using a partial filling technique and α1-acid glycoprotein as chiral selectorglycoprotein as chiral selector[J] 1997,Chromatographia(3-4):119~128
  • 2J. M. Lin,T. Nakagama,K. Uchiyama,T. Hobo. Molecularly imprinted polymer as chiral selector for enantioseparation of amino acids by capillary gel electrophoresis[J] 1996,Chromatographia(11-12):585~591
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  • 4R. Kuhn,F. Stoecklin,F. Erni. Chiral separations by host-guest complexation with cyclodextrin and crown ether in capillary zone electrophoresis[J] 1992,Chromatographia(1-2):32~36

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