全国21家医院急性肺栓塞诊治情况的调查分析

Survey of diagnosis and treatment of acute pulmonary embolism in 21 hospitals in China

目的 初步了解我国部分医院急性肺栓塞的诊治情况。方法 1 997年 8月至 1 999年 7月在全国 2 1家医院开展了“急性肺栓塞尿激酶溶栓 (栓复欣抗凝 )治疗多中心临床试验” ,各医院对试验期间确诊的急性肺栓塞患者填表登记 ,记录其基本情况和诊断、治疗情况。试验结果后收集登记表进行统计分析。结果 2年间 2 1家医院诊断急性肺栓塞 2 97例 ,溶栓治疗总有效率 80 8% ( 2 3 1 /2 86) ,病死率 9 8% ( 2 8/2 86)。结论 急性肺栓塞是一常见疾病 ,增强诊断意识是减少误、漏诊的关键 ,溶栓治疗是有效的急救措施。

Objective To understand the diagnostic and therapeutic status of acute pulmonary embolism in China. Methods Clinical data of 297 patients with acute pulmonary embolism were registered in 21 hospitals in China that participated in the 'multicenter clinical trial on the efficacy of thrombolytic therapy with urokinase and/or anticoagulation with low molecular weight heparin (Fluxum) in patients with acute pulmonary embolism' from August 1997 to July 1999. Results 297 patients with acute pulmonary embolism were diagnosed and treated in the 21 hospitals during 2 years. The total effective rate of thrombolytic therapy was 80.8% (231/286), and the mortality rate was 9.8% (28/286). Conclusion Acute pulmonary embolism is a common disease. In order to decrease the rate of misdiagnosis and missed diagnosis it is necessary to raise the consciousness of diagnosis. Thrombolytic therapy is an effective first aid meaure.