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应激大鼠褪黑素受体改变及意义 被引量:2

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摘要 目的 :探讨应激状态下褪黑素受体 (MR)的改变及意义。方法 :将 SD大鼠分为溃疡性结肠炎、脑缺血、出血性休克、褪黑素预处理及对照组 ,应用放射配体结合法检测大鼠脾脏 MR。结果 :大鼠应激后脾脏组织 MR特异结合降低 ;褪黑素可提高溃疡性结肠炎、脑缺血、出血性休克组大鼠生存率。 结论 :应激状态 MR特异结合降低 。
出处 《第二军医大学学报》 CAS CSCD 北大核心 2001年第11期1074-1075,共2页 Academic Journal of Second Military Medical University
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同被引文献17

  • 1邱勇,吴亮,王斌,俞扬,朱泽章,钱邦平,马薇薇.特发性脊柱侧凸双侧椎旁肌褪黑素受体含量的差异性比较研究[J].中华外科杂志,2006,44(12):826-829. 被引量:6
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  • 6Arck PC,Sloinski A,Theoharide TC,et al.Neuroimmunology of stress:skin takes center stage.J Invest Dermatol,2006,126(8):1697-1704.
  • 7CarriUo-vico A,Reiter RJ,Urdone PI,et al.The modulatory role of melatonin on immune responsiveness.Curr Opin Investing Drugs,2006,7(5):423-431.
  • 8Pugazhenthi K,KapoorM,Clarkson AN,et al.Melatonin accelerates the process of wound repair in full-thickness incisional wounds.J Pineal Res,2008,44(4):387-396.
  • 9Yildirim Z,Kotuk M,Erdogan H,et al.Preventive effect of melatonin on bleomycin-induced lung fibrosis in rats.J Pineal Res,2006,40(1):27-33.
  • 10Turgut M,Uysal A,Pehlivan M,et al.Assessment of effects of pinealectomy and exogenous melatonin administration on rat sciatic nerve suture repair:an electrophysiological,electron microscopic,and immunohistochemical study.Acta Neurochir,2005,147(1):67-77.

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