血管免疫母细胞淋巴结病23例临床分析

Clinical analysis of 23 cases of angioimmunoblastic lymphadenopathy with dysproteinemia (AILD)

目的 通过对血管免疫母细胞淋巴结病 (AILD)临床表现的分析 ,为 AIL D的诊断和治疗提供依据。方法 回顾性分析近 15年收治的 2 3例 AILD住院患者的各项临床资料。结果 AIL D临床表现多样 ,可累及多脏器 ;确诊需淋巴结活检 ,而反应性淋巴结增生与 AIL D关系密切 ;此病预后差 ,积极治疗可延长生存期。结论 临床考虑 AIL D时 ,多次淋巴结活检是必要的。治疗上宜采用联合化疗并加

Objective To improve the diagnosis and therapy of AILD by analysing the clinical features of AILD.Methods To analyse 23 patients with AILD,admitted to PUMC hospital in the recent 15 years.Results AILD has the broad clinical spectrum which of ten presents with multiple organ impairment.Only lymphaden biopsy could establish the confirmative diagnosis.Reactive lymphaden hyperplasia is closely correlated with AILD.Appropriate therapy could prolong the patient's surviual despite poor prognosis.Conclusions Repeated lymphaden biopsy is necessary if AILD is considered.Conbined chemotherapy with α interferon is acceptable in the treatment of AILD.