补肺健脾颗粒对小鼠免疫功能的影响

Influence of Bufei Jianpi Granule on Immune Function in Mice

[目的 ]探讨补肺健脾颗粒对小鼠免疫功能的影响。 [方法 ]测定补肺健脾颗粒对小鼠脾细胞增殖反应及IL -1、IL -2活性。 [结果 ]补肺健脾颗粒组脾细胞对ConA刺激的增殖反应、脾细胞产生IL -2和腹腔巨噬细胞产生IL -1的作用与生理盐水组和玉屏风散组相比均具有显著性差异。 [结论 ]补肺健脾颗粒对细胞免疫和免疫活性细胞分泌IL -1和IL -2的功能有促进作用。

To investigate the influence of Bufei Jianpi Granule (BJG) on immune function in mice. Spleen cellular proliferation and the activities of IL-1 and IL-2 in mice were observed. The differences of spleen cellular proliferation stimulating by Con A, the secretion of IL-2 from spleen cells and the secretion of IL-1 from celiac macrophage were significant among BJG group, the control group and the water-drinking group. [Conclusion] BJG can promote the function of cellular immune and the secretion of IL-1 and IL-2 from immune active cells in mice.