摘要
目的 :研制磺胺嘧啶银 (SD -Ag)胶原蛋白烧伤膜 ,建立了分光光度法测定SD -Ag的累积释放量的大小 ,为进一步开发胶原蛋白膜剂提供经验。方法 :应用交联剂法制备胶原蛋白烧伤膜 ,采用均匀设计方案 ,考察累积释放量的大小。结果 :制备后得到乳白色半透明、光滑 ,具有弹性的凝胶膜状物。胶原蛋白膜的累积释放量为 (22 38±0 036) %。结论 :用交联剂法制备胶原蛋白膜简便 ,便于铸型 ,成膜性好。本方法准确、快速、简便 ,可用于SD -Ag
AIM:To prepare the sulfadiazine silver collagen sheeting for burn(SD-Ag sheeting) and determine the release rate of sulfadiazine silver METHODS:To prepare the SD-Ag sheeting by cross-linking method and to determine the release rate by uniform design RESULTS:The release rate of SD-Ag from SD-Ag sheeting was (22 38±0 036)% CONCLUSION:The preparation of SD-Ag sheeting by cross-linking method was convenient The determining method was accurate,rapid and simple for the quality control of the SD-Ag sheeting
出处
《中国药房》
CAS
CSCD
2001年第7期394-395,共2页
China Pharmacy
基金
全军"九五"课题基金项目 (41A17)
关键词
磺胺嘧啶银胶原蛋白烧伤膜
累积释放量
交联剂法
分光光度法
sulfadiazine silver collagen sheeting for burn
accumulated release amount
cross-linking method
spectrophotometry