摘要
目的 :研制盐酸左旋氧氟沙星滴耳液。方法 :采用紫外分光光度法测定含量。结果 :线性范围为2～10μg/ml,回收方程为A=1.83×10—3+0.07415C ,r=0.9991(n=5) ;该方法测得平均回收率±标准差为 (98.74±0.51) %。结论:该滴耳液抗菌作用强 ,质量稳定 ,紫外分光光度法测定含量方法简便、快速。
OBJECTIVE:To prepare levofloxacin hydrochloride ear drops METHODS:The content of levofloxacin hydrochloride was determined with UV-spectrophotometry RESULTS:The linearity range was 2～10μg/ml with a regression equation of A=1 83×10-3+0 07 415C and r=0 9 991(n=5) The average recovery was (98 74±0 51)% CONCLUSION:The UV-spectrophotometry method is simple,rapid and accurate and the preparation is powerful in antibacterial action and stable in quality
出处
《中国药房》
CAS
CSCD
2001年第7期404-405,共2页
China Pharmacy
关键词
盐酸左旋氧沙星
滴耳液
制备
质量控制
levofloxacin hydrochloride
ear drops
preparation
quality control
