摘要
目的 :研究复方洛美沙星滴鼻液的制备和该制剂的质量控制标准。方法 :采用紫外一阶导数法不经分离直接测定洛美沙星含量 ,测定波长为293nm和315nm。结果 :相关系数为r=0 9999 ,平均回收率为100 77 % ,RSD为0 82 %。结论 :该制剂制备容易 ,以一阶导数光谱法测定洛美沙星含量 ,方法简便、快速。
OBJECTIVE:To study the preparation and the quality control of the compound lomefloxacin nose-drops MET_HODS:The first order derivative spectrophotometry was used to determine the content of lomefloxacin with no need of isolation The detecting wavelengths were 293nm and 315nm RESULTS:The correlation coefficient was 0 9 999 The average recovery was 100 77%,with RSD of 0 82% CONCLUSION:The preparation process of compound lomefloxacin nose-drops was simple,the first order derivative spectrophotometry for the determination was rapid,simple and accurate
出处
《中国药房》
CAS
CSCD
2001年第7期406-407,共2页
China Pharmacy
关键词
洛美沙星
滴鼻液
制备
质量控制
lomefloxacin
nose-drops
preparation
quality control
