中西医结合治疗伤寒112例临床观察

Clinical Observation on the Treatment of Typhoid with Combined TCM and WM,a Report of 112 cases

选符合伤寒诊断标准住院患者 176例 ,随机分为治疗组 112例 ,对照组 6 4例。治疗组予氯霉素等西药常规治疗加中药辨证施治 ,对照组仅予西药治疗。结果 :治疗组痊愈 10 8例 ,无效 (并发症 ) 4例 ,痊愈率为 96 .43% (95 % CI=90 .48%～98.6 6 % ) ;对照组痊愈 5 9例 ,无效 5例 ,痊愈率为 92 .19% (95 % CI=85 .6 2 %～ 98.76 % ) ,两组痊愈率比较 ,有统计学差异 (χ2= 7.6 912 ,P<0 .0 1)。治疗组较对照组并发症发生的危险性明显降低 ,OR=0 .44 (95 % CI=0 .16～ 0 .6 5 ) ,每治疗 2 4人可减少1人发生并发症 ,NNT=2 4(95 % CI=16～ 38) ;且退热时间、住院时间、氯霉素用量也显著减少 (u=4.775 3、2 .7986、4.2 90 6 ,P<0 .0 1)。

One hundred and seventy six cases of typhoid were randomly divided into two groups:112 in the treatment group and 64 in the control group.In the treatment group patients were treated with combined WM and TCM,while in the control group patients treated only with chloramphenicol.Result:In the treatment group 108 cases were cured,4 cases ineffective and the cure rate was 96.43%(95% CI=90.48%～98.66%);In the control group it respectively was 59,5,92.19%(95%CI=85.62%～98.76%).The difference of cure rate was significant(χ 2=7.6912,P<0 01) Oceurrence of complication in the treatment group decreased,OR=0 44(95% CI=0 16～0 65),NNT=24(95% CI=16～38);antifebrile time,hospitalization time,and chloramphenicol dosage also significantly decreased (u=4.7753,2.7986,4.2906,P<0 01)