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Invader分析——一种新的核酸检测技术 被引量:2

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摘要 Invader分析使用一个耐热的、结构特异的内切核酸酶 ,根据结构而不是序列在特殊位点上切割核酸分子。是一种等温非“PCR”的DNA和RNA定性和定量检测方法。可简单、快速、准确检测基因突变和单核苷酸多态性 (SNPS)。在感染性疾病、遗传性疾病诊断及治疗药物选择发挥了重要作用。
机构地区 解放军沈阳
出处 《国外医学(临床生物化学与检验学分册)》 2001年第6期293-294,共2页 Foreign Medical Sciences(section of Clinical Biochemistry and Laboratory Medicine
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参考文献10

  • 1KwiatkowskiRW,,LyamichevV,ArrudaM,etal.Clinical,genctic.andpharmacogencticapplicationsoftheInvaderassay[].MolDiage.1999
  • 2Francesco LD.The next new wave in genome analysis: Invader assays developed by third wave[].The Scientist.1998
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  • 7Agarwal P,Oldenburg MC,Czarneski JE,et al.Comparison study for identifying promoter allelic polymorphism in interleukin 10 and tumor necrosis factor alpha genes[].Diagnostic Molecular Pathology.2000
  • 8Cooksey RC,Holloway BP,Oldenburg MC,et al.Evaluation of the invader assay a linear signal amplification method,for identification of mutations associated with resistane to rifampin and isoniazid in Mycobacterium tuberculosis[].Antimicrobial Agents and Chemotherapy.2000
  • 9Wilkomson DA.Third wave technologies’s invader assays for nucleic acid detection[].The Scientist.1993
  • 10Mein Ca,Barratt BJ,Dunn MG,et al.Evaluation of single nucleotide polymorphism typing with invader on PCR amplicons and its automation[].Genome Research.2000

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