摘要
利用红外光谱和核磁共振氢谱对魔芋葡甘低聚糖醛酸丙酯硫酸酯钠的结构进行了分析，表明合成 物结构与试验设计相吻合．利用凝胶色谱法测定其数均相对分子质量为 ２ ７７５，重均相对分子质量为 ３ ５７７， 表明合成物的相对分子质量位于低分子类肝素的分子质量范围．利用硫酸钡浊度法测定其硫酸基含量，表明 合成物硫酸基平均含量４６．５４％（ＲＳＤ＝０．５６％）．
A newly synthesized heparinoid-Hydroxypropyl oligo-glucomannuronate sulfate with its struc- tural analysis is reported. The results of IR and H-NMR spectrometry show that it possesses the structure of heparinoid, which accords with the preceding design. The result of GPC reveals its molecular weight be- ing 3 000-4 000 u, which is in the scope of low molecular weight heparinoid. Its sulfur content is deter- mined by barium sulfide turbidity analysis, with the sulfur content being 46. 5%.
基金
湖北省科技厅重点攻关项目(991P1402-7)
