急性心肌梗死患者血清C反应蛋白与CK-MB相关性研究

Relationship Between Serum C-Reactive protein and Creatine Kinase Isoenzyme in Acute Myocardial Infarction

对 5 2例急性心肌硬死 (AMI)患者的不同时间的CK -MB和CRP浓度进行测定。结果发现 ,AMI后 1 2hCK -MB与CRP的阳性率分别为 1 0 0 % ,44 2 % ;48h为 5 7 7% ,86 5 %。动态观察发现CK -MB和CRP的峰值分别出现在 1 2h和 48h。表明CRP对亚急性心肌梗死的诊断优于CK -MB。

Objective To investigate the relationship between serum c-reactive protein(CRP) and creatine kinase isoenzyme (CK-MB) in the diagnosis of acute myocardial infarction (AMI). Methods We assessed the serum CK-MB and CRP concentration in 52 patients with definite AMI at different time after their infarction. Results 12 hours after infarction there were 100% and 44.2% patients with positive results in CK-MB and CRP respectively, and 48 hours are 57.7% and 86.5%. By continous observation we found that the peaks of CK-MB and CRP occurred respectively at 12 hours and 48 hous after infarction. Conclusion It is suggested that as a diagnostic marker CRP is superior to CK-MB in sabacent myocardial infarction patients.